A new study done by experts at The University of Texas MD Anderson Cancer Centre provides a deeper understanding of the development of the tumour microenvironment throughout the progression of gastric cancer. Two of the study's notable discoveries include a potential therapeutic target and a link between multicellular communities and clinical outcomes, which were published in Cancer Cell.

Gastric adenocarcinoma is one of the most lethal cancers in the world due to its inherent resistance to therapy, yet little is understood about the cellular and molecular pathways that lead from early pre-cancer to tumour growth and dissemination. This research explains how distinct immune and stromal cell subsets alter as stomach cancer progresses.